Hey Trisha, your post entails lots information for people who are experiencing infertility over the 40. honestly, I am one of those, struggling for nearly nine years. But have pursued surrogacy. I know keeping calm dent work in some cases. Countless times felt like a failure, guilty being infertile and what not. Yeah, disparity nature does hit hard. My friend conceived at the age of 45 and naturally. Whereas, I failed several times. Done three cycles of IVF, IUI, which failed miserably. Also, had three CP’s. After trying for years, now I am anticipating for my surrogate to fall pregnant.I would say, giving up doesn’t do any good. There is time for everything. There is nothing definite resolution for everyone. One won’t knows it unless tried.