There are several issues that must be kept in mind when discussing ovarian reserve and its impact on infertility. First, decreasing ovarian reserve is a normal part of the aging process. Although some studies have suggested that diminished ovarian reserve. As measured by the cycle day 3 FSH, is a better predictor of infertility therapy success. Most Reproductive Endocrinologists would agree that age is still the number one factor that compromises a woman’s ability to become pregnant. Age and diminished ovarian reserve are usually synonomous, but not always. In looking at the success of standard infertility therapy. All other things being equal, the older the woman, the less likely she is to become pregnant. One study looked at a large number of women with unexplained infertility who were going through super ovulation using Clomid combined with IUI.